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Brewer, D. D., & Khan, A. A. (2010). HCV and HIV prevalences strongly correlated in Asian communities with reservoirs of HIV in high-risk groups. Journal of Infection in Developing Countries, 4, 442-447.

abstract     full article

Background: In some Asian communities, HIV epidemics initially concentrated in high-risk groups develop into generalized epidemics, while in others HIV epidemics remain confined to high-risk groups. We examined whether blood exposures in a community, as indicated by hepatitis C virus (HCV) prevalence, can account for the variability in HIV prevalence in Asia.

Methodology: We searched the published literature for temporally comparable HCV and HIV prevalence estimates for pregnant women and other “low-risk” population segments in Asian communities with established HIV epidemics in injection drug users or prostitute women. We assessed the correlation between HCV and HIV prevalences in these communities.

Results: HCV and HIV prevalences were strongly correlated (r = .97, p < .001).

Conclusion: This finding suggests that blood-borne transmission drives generalized HIV epidemics in Asia and highlights the need for appropriately designed investigations of transmission modes.


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